FGFR2 and craniosynostosis: Approximately 1 in 2000–2500 children of all ethnic groups are born with craniosynostosis conditions (Heuzé et al., 2014; Lajeunie et al., 2006) and though variants of many genes are associated with these disorders (Cuellar et al., 2020; Calpena et al., 2020; Goos and Mathijssen, 2019; Holmes et al., 2021; Justice et al., 2012; Maruyama et al., 2021; Wilkie, 1997; Wilkie and Morriss-Kay, 2001), alteration to the function of fibroblast growth factor receptor 2 (FGFR2) results in the more common craniosynostosis syndromes of Apert, Crouzon, and Pfeiffer.