LEP and obesity due to melanocortin 4 receptor deficiency: A greater chance of obesity was observed in patients who had leptin AA/AG haplotypes (rs7799039) (OR 3.9; 95% CI 1.4–12.1; p=0.003) and adiponectin (rs17300539) (OR 8.4; 95% CI 1.8–72.2; p=0.001) when compared to GG haplotypes, but not significant for patients’ TNF-α haplotypes (Table 3).