ENHO and coronary atherosclerosis: At the same time, it was reported that adropin levels are inversely proportional to the severity of coronary atherosclerosis.18 It is known that adropin is involved in the regulation of endothelial function.19 There is an association between decreases in its level and endothelial dysfunction and metabolic syndrome.20 Similarly, it has been stated that low circulating adropin levels in patients with type 2 DM are a risk factor for endothelial dysfunction.21