In AML; FLT3 (4 times), DNMT3A (3), NPM1 (3), IDH2 (2), NRAS (2), TP53 (2), ASLX1 (2), IDH1 (1), EZH2 (1), TET2 (1), KRAS (1), and SF3B1 (1) mutations were detected. This evidence concerns the gene EZH2 and acute myeloid leukemia.