TNC and cancer: For instance, elevated expression of syndecan‐2 (SDC‐2) has been correlated with increased invasiveness in various types of cancers, including fibrosarcoma,16 melanoma,17 colon,18 pancreatic19 and colorectal20 cancers, while TN‐C is overexpressed in brain tumours,21 breast,22 lung23 and colorectal24 cancers.