WWTR1 and cancer: In solid tumours, high YAP/TAZ activity in general increase the risk of metastasis (Steinhardt et al, 2008; Lamar et al, 2012), impede cancer treatment and confer poor prognosis (Moroishi et al, 2015a; Rognoni & Walko, 2019; Salem & Hansen, 2019; Zanconato et al, 2019; Thompson, 2020).