The results revealed that the essential oil in leaves of C. grandis ‘Tomentosa’ could potentially treat tumors, immune diseases, neurodegenerative diseases and respiratory diseases by multi-pathways and multi-targets in which the most promising evidence was that farnesol might treat cognitive impairment and chronic obstructive pulmonary disease by regulating apoptosis via targeting CHRM1. Here, CHRM1 is linked to immune system disorder.