CHRM1 and Cognitive impairment: The results revealed that the essential oil in leaves of C. grandis ‘Tomentosa’ could potentially treat tumors, immune diseases, neurodegenerative diseases and respiratory diseases by multi-pathways and multi-targets in which the most promising evidence was that farnesol might treat cognitive impairment and chronic obstructive pulmonary disease by regulating apoptosis via targeting CHRM1.