Some of the peptides give a signal during specific disease state transitions, i.e. they differ between an infected and uninfected individual (such as peptides from the complement-related protein SERPING1 or the iron-binding protein TF (Figure 3a, Figure 3b)), or change the most during the most severe treatment escalations of COVID-19 (such as the kidney and inflammation marker CST3 (Figure 3a, Figure 3b)). This evidence concerns the gene CST3 and COVID-19.