TP53 and hepatocellular carcinoma: The enrichment results of the top 20 KEGG pathways are shown in Table S2, including the metabolic pathway, cell cycle, DNA replication, focal adhesion, ECM-receptor interaction and signaling pathways (p53, PI3K (phosphatidylinositol 3′ -kinase)-Akt, PPAR (Peroxisome proliferator-activated receptor)) which had been reported to be associated with HCC.