ALK and neoplasm: To investigate the conditions under which tumor cells can be induced to a quiescent state in a few days, we used a human anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) cell line H2228 because ALK-rearranged NSCLC patients treated with ALK tyrosine kinase inhibitors are known to have frequent cancer recurrence12.