To understand more about the critical factors that are decisive for the two major glioblastoma subtypes, we used two cell lines that were produced in an earlier study: cell line U-2982MG with stable overexpression of SOX2 (U-2982MG/SOX2), and cell line U-2987MG with stable overexpression of SFRP2 (U-2987MG/SFRP2). Here, SOX2 is linked to glioblastoma.