Patients with severe thrombocytopenia displayed significantly higher expression levels of MLKL and Beclin-1 than those who had moderate thrombocytopenia (4.03 ± 0.63 and 4.73 ± 0.56 vs 1.54 ± 0.22 and 1.99 ± 0.33, respectively) (Fig. 2a). This evidence concerns the gene BECN1 and Thrombocytopenia.