Moreover, there were positive correlations between MLKL (rpb = 0.360; P = 0.01), RIPK3 (rpb = 0.413; P = 0.005), Beclin-1 (rpb = 0.453; P = 0.002) mRNA levels and severity of bleeding in ITP patients (Table 3). The gene discussed is BECN1; the disease is autoimmune thrombocytopenic purpura.