TOR1A and Dystonia: The tactile temporal discrimination threshold (TDT) is increased in different types of isolated dystonia, nonmanifesting DYT1-mutation carriers, and unaffected relatives of both familial and sporadic adult-onset dystonia patients, and the somatotopic representation of fingers in the S1 cortex was disorganized on both sides in unilaterally affected dystonic patients (Meunier et al., 2001).