LZTR1 and schwannoma: One patient from Japan presenting with a left intraorbital schwannomas and multiple spinal schwannomas was tested and found to be SMARCB1 and LZTR1 negative [43], while another Japanese family – father and son pair with the father presenting with thoracic spinal and cutaneous schwannomas and his 35-year old son with a left cerebropontine angle schwannoma—were found to carry SMARCB1 pathogenic variants [41].