Conditions that did not receive a suggested diagnosis, are represented by Hartsfield syndrome (HRTFDS, MIM#615456), a very rare malformation condition with holoprosencephaly, ectrodactyly, and cleft/lip palate, and Kleefstra syndrome 1 (KLEFS1, MIM#610253). Here, EHMT1 is linked to Hartsfield-Bixler-Demyer syndrome.