PCLAF and common cold: A rat model of PAF-induced rhinosinusitis has been successfully established by Jeon et al. where the presence of neutrophil clusters in nasal cavity, infiltration of polymorphonuclear cells in mucosa, goblet cell hyperplasia in the epithelium and epithelial damage were observed after one-time intranasal administration of 16 μg/ml PAF at 50 μl [39].