Regarding endometriosis patients GnRH-a pretreatment (conventional medication: One injection of long-acting (3.75 mg per tube) leuprolide for 7–21 days during menstruation, or short-acting leuprolide (0.1 mg per tube) daily from 7–21 days of menstruation to the day of ovulation induction), a total of 5 articles [33–37] were included, with 10 sets of data (the total number of sample cases n = 1099, 10 groups of self-control studies) (Table S3). The gene discussed is GNRH1; the disease is endometriosis.