CREBBP, a gene known to be altered in response to COVID-19 infection, and hsa-miR-483-3p were not only differentially expressed in patients with COVID-19 but also had an inverse interrelation using mirTarRnaSeq (adjusted p value = 0.03 and miRanda score 173 (range [140 -189]) concordant with the results obtained from the lung covid infection experiment [46]. This evidence concerns the gene CREBBP and infection.