Jiren Zhang et al. [34] proposed a risk score system for pancreatic adenocarcinoma based on CEBPA and other 11 methylation genes (HIST1H4E, STAMBPL1, PLD3, CEP55, SSBP4, GRIA1, SWAP70, ADCYAP1R1, YPEL3, HOXC4, and IGFBP1), suggesting that CEBPA might be critical for the survival of PDAC. Here, PLD3 is linked to pancreatic adenocarcinoma.