ADCYAP1 and migraine disorder: In the patients in the ictal period, there was a tendency for plasma PACPA-38 levels to be elevated in the migraine patients with aura, but no difference was observed between the two groups (Fig. 5b) (PACAP-38(MWA) = 41.46 ± 4.56 ng/ml, PACAP-38(MWoA) = 41.06 ± 5.16 ng/ml, p > 0.05).