TNFSF11 and ductal breast carcinoma in situ: In addition, in five out of seven OGC-IC NST cases harboring a ductal carcinoma in situ (DCIS) component, we observed RANK-L positivity in the associated DCIS (Fig. 4B, K), but only in one DCIS out of six IC TNS without OGC; statistical tests for this comparison could not be performed due to the small sample size.