Another study that compared SARS-CoV-2 with Ebola virus, H1N1 influenza virus, MERS-CoV and SARS-CoV found that genetic pathways associated with hepatitis B, the AGE-RAGE signaling system, malaria, influenza A and rheumatoid arthritis were the most significant pathways altered upon infection36. This evidence concerns the gene RENBP and rheumatoid arthritis.