These included: (i) 27 novel eGFR loci in DM, and (ii) two of the four previously identified DKD loci among type 1 or type 2 DM patients22 (near UMOD/PDILT and PRKAG2; r2 = 0.60 and 0.94, respectively, between eGFR and DKD lead variants). This evidence concerns the gene PRKAG2 and diabetes mellitus.