Among the 34 novel eGFR variants, four showed a suggestive DM/noDM-difference for eGFR (PDiff < 0.0015 = 0.05/34, Table 2, Fig. 3b): one was a DM-only effect (near SH3BP4) and three showed more pronounced effects in DM (near LOXL4, ALPL, and PIK3CG). The gene discussed is LOXL4; the disease is diabetes mellitus.