For example, the CFH variant rs570618 at 1q31.3, which is a proxy for the CFH Y402H (aka rs1061170) missense mutation, was linked to AMD risk (Supplementary Data 7) and is associated with 217 serum proteins, 100 of which are found in PM13 (Supplementary Data 8 and 11). Here, CFH is linked to age-related macular degeneration.