We analyzed genetic variations in KDM2A in 1916 bladder cancer cases retrieved from six studies (476 cases from Memorial Sloan Kettering [MSK]/The Cancer Gene Atlas [TCGA], 2020; 413 cases from TCGA, Cell 2017; 131 cases from TCGA, Nature 2014; 413 cases from TCGA, Firehose Legacy; 411 cases from TCGA, PanCancer Atlas; and 72 cases from Cornell/Trento, Nat Gen 2016). This evidence concerns the gene KDM2A and urinary bladder cancer.