Differentiated control and C9-ALS/FTLD iPSC motor neuron cultures (2 control lines & 3 C9-ALS/FTLD lines; Supplementary Table 1) were assessed at 89 days post-differentiation39 and immunostained for NUP62 and MAP2 (Fig. 1e). Here, NUP62 is linked to amyotrophic lateral sclerosis.