CD274 and melanoma: demonstrate that the epigenetic modifiers Entinostat and Vorinostat enhanced γδ T cell cytotoxicity and chemotaxis against MPDOs, through the downregulation of PD‐1, upregulation of CXCR3/CD107a expression, IFNγ production in combination with the MICA/B upregulation and PD‐L1 downregulation in melanoma cells.2