GPT and Hepatic fibrosis: In the univariate analysis, male sex (OR, 1.37; 95% CI, 1.22-1.55; P < .001), higher ALT levels (OR, 1.01; 95% CI, 1.01-1.01; P < .001), higher serum HBV DNA levels (OR, 1.32; 95% CI, 1.28-1.35; P < .001), coexistence of HBsAg and anti-HBs (OR, 2.01; 95% CI, 1.56-2.58; P < .001), HBeAg positivity (OR, 2.23; 95% CI, 1.99-2.51; P < .001), and the interaction between HBeAg and anti-HBs (OR, 2.57; 95% CI, 1.79-3.70; P < .001) were associated with severe liver fibrosis (Table 4).