MKI67 and large cell neuroendocrine carcinoma: The Ki-67 indices of ACs varied from 4.1 to 12.5% or from 3.6 to 9.9% depending on whether they were calculated according to the 2019 WHO classification of GEP-NETs [23] or the 2018 WHO consensus proposal [24] for a common classification framework for neuroendocrine neoplasms (NEN), respectively, whereas the Ki-67 index of the LCNEC was 16.5 or 20.3%, respectively [Table 4].