In the USA, over 90% of patients with CGD are on prophylactic antibiotics (usually trimethoprim-sulfamethoxazole), about 70% are on prophylactic antifungals, but only about 35% are on interferon gamma, likely due to intolerance (which has not been a major problem in our patients), cost or lack of access. Here, IFNG is linked to chronic granulomatous disease.