MAPT and tauopathy: Furthermore, cell-to-cell transmission of distinct pathological species of αSyn (Jan et al. 2021; Brás and Outeiro 2021) and tau (Brunello et al. 2020) in a so-called “prion like manner” is considered to be the mechanism behind the progression of synucleinopathies and tauopathies throughout the brain (Uemura et al. 2020).