Furthermore, cell-to-cell transmission of distinct pathological species of αSyn (Jan et al. 2021; Brás and Outeiro 2021) and tau (Brunello et al. 2020) in a so-called “prion like manner” is considered to be the mechanism behind the progression of synucleinopathies and tauopathies throughout the brain (Uemura et al. 2020). This evidence concerns the gene MAPT and synucleinopathy.