The co-expression of cytokine and receptor genes (CCL2-CCR2,CCL3-CCR1, CCL3-CCR5,CCL4-CCR5, CCL4L2-VSIR, and CCL3L1-CCR1) confirmed that cytokine–receptor axes found in COVID-19 may also play a critical role in TEX of LUSC. The gene discussed is CCL4; the disease is COVID-19.