NLRP3 and myeloid sarcoma: After migration, primed T cells play an important role in the course of the disease, and the NLRP3 inflammasome, in both T cells and microglia, has been reported to induce T cells to release proinflammatory cytokines involved in the pathogenesis of MS (Inoue et al., 2012a; Olcum et al., 2020).