The essential role of BMP4 in erythroid cell development (Porayette and Paulson, 2008) and its ability to regulate vital processes, such as angiogenesis and hematopoiesis (Goldman et al., 2009; Ciais and Bailly, 2012) have made this signaling molecule an increasingly interesting topic in cancer research (Kallioniemi, 2012). This evidence concerns the gene BMP4 and cancer.