IL1B and Mental deterioration: Resveratrol has been used to suppress the activation of nuclear transcription factor-kappa B (NF-kB) and the production of prostaglandins (42), reducing the expression of interleukin 1 beta (IL-1β) and TNF-α factor (4, 43), increase the activity of the telomerase enzyme, involved in the prevention of cellular senescence and delay of cognitive decline (44), or promote the activity of sirtuins and peroxisome proliferator-activated receptor-γ co-activator 1-α (PGC-1α) (4, 45).