MCM2 and cancer: The mRNA expression level of MCM2 was markedly upregulated in patients with 33 cancers (p < 0.05), including ACC, BLCA, BRCA, CESC, CHOL, COAD, DLBC, ESCA, GBM, HNSC, KICH, KIRC, KIRP, LAML, LGG, LIHC, LUAD, LUSC, OV, PAAD, PRAD, READ, SKCM, STAD, TGCA, THCA, THYM, UCEC, and UCS (Figure 2A).