CLCA4 and colorectal cancer: Previous studies have shown that the increase of CLCA1 and CLCA4 levels in tumor tissue is related to the excellent prognosis of colorectal cancer patients, consistent with our survival analysis (Chen et al., 2018; Pan et al., 2019a; Pan et al., 2019b; Chen et al., 2019; Wei et al., 2020a; Wei et al., 2020b).