Although TGF-β-induced EMT may render breast cancer cells with stem cell properties, BMPs, particularly heterodimeric BMP-2/7, antagonize TGF-β-induced EMT and reduce the aldehyde dehydrogenase (ALDH)h CD44h CD24l− CSC population (Buijs et al., 2012). This evidence concerns the gene CLN5 and breast carcinoma.