Due to the importance of IL-23 production in dendritic cells (DCs), we grouped the keratinocyte clusters (KC-S.corneum, KC-S.granulosum, KC-S.spinosum, and KC-S.basale for GSE151177; KC-S.basale-1, KC-S.basale-2, KC-S.basale-3, KC-S.granulosum, and KC-Activated for GSE162183) and DC clusters (immature and mature DC for GSE151177; DC for GSE162183) for the comparison of IL23A expression. The gene discussed is CALCA; the disease is keratoconus.