NLRP3 and systemic lupus erythematosus: The latest evidence shows that the expression of NLRP3 inflammasome-related constituents expression were elevated in various cells, including bone marrow-derived mesenchymal stem cells and monocytes/macrophages, in patients with SLE, such as bone marrow-derived mesenchymal stem cells and monocytes/macrophages, and even the content of active caspase-1 in monocytes was positively correlated with the serum titer of anti-double stranded DNA antibodies (anti-dsDNA Abs) (104, 105).