Galectin-9 mRNA was also increased in peripheral blood mononuclear cells from DM and anti-MDA5 positive adult-onset patients and correlated with the type I IFN inducible genes MX1 (MX dynamin like GTPase 1) and IFIH1 (interferon induced with helicase C domain 1) (47). This evidence concerns the gene MX1 and dermatomyositis.