Another study showed that lncRNA growth-arrest-specific transcript 5 (GAS5) induced SMC apoptosis and subsequent abdominal aortic aneurysm (AAA) by activating the zeste homolog 2 (EZH2)-mediated RIG-I signaling pathway in angiotensin II-induced AAA mouse models (71). Here, EZH2 is linked to triple-A syndrome.