CD8A and lymphoma: By screening a library encompassing chemically differing lipid-like formulations, termed lipidoids, Zhao and coworkers showed that lipidoids with an imidazole group yielded stronger reporter mRNA transfection efficacies of primary human CD8+ T cells in vitro (77), and was suitable for transfer of CAR-T mRNA into CD8+ T cells as reflected from potent killing activity of lymphoma cells (78).