FGF2 and systemic sclerosis: Also FGF2 mRNA relative expression was reduced in 1,25(OH)2D3 treated cells in a dose-dependent manner (from 2.38-fold in SSc untreated cells to 2-fold in 10-9M, p<0.05; to 1.75-fold in 10-8M p<0.01; to 1.3-fold in 10-7M, p<0.001 compared to control).