CCN2 and systemic sclerosis: Compared to healthy subjects, SSc derived PBMCs also showed a greater production of FGF2 (15.77±5.18 pg/ml vs 8.9±1.5 pg/ml), TGFβ (784.1±239.6 pg/ml vs 663.7±84.9) and CTGF (105.2±14.1 pg/ml vs 80.1±11.4 pg/ml) (Table 2).