NPNT and myocardial infarction: On day 28 post MI surgery, Masson trichrome staining were applied to assess myocardial interstitial fibrosis (see in Figure 2B-2C) and our results illustrated that NPNT overexpression ameliorated myocardial interstitial fibrosis (11.4 ± 2.6% vs. 19.1 ± 1.6%, P < 0.05) compared with MI-PBS group, namely in border zone after MI.