The study of Gao et al. demonstrated the G2/M arrest of tongue squamous cell carcinoma cells induced by inhibition of CKS2 expression, and the regulatory effect of CKS2 on the cell cycle progression of tongue squamous cell carcinoma cells was linked with the interaction between CKS2 and DUTPase [24]. This evidence concerns the gene CKS2 and tongue squamous cell carcinoma.