TOP2A and adrenal cortex carcinoma: In TCGA-ACC data, ASPM (F = 6.939, p = 0.001), BIRC5 (F = 3.368, p = 0.034), CCNB2 (F = 4.844, p = 0.009), CDK1 (F = 6.779, p = 0.001), DLGAP5 (F = 4.170, p = 0.014), FOXM1 (F = 7.569, p = 0.001), RACGAP1 (F = 4.717, p = 0.009), TOP2A (F = 4.687, p = 0.008), and TPX2 (F = 5.232, p = 0.005) were significantly associated with tumor stage (Supplementary Table S6).