This syndrome, linked to the CSNK2B gene located on chromosome 6 (6p21.33), now termed the Poirier-Bienvenu Neurodevelopmental Syndrome (POBINDS), has been described in 51 patients (Sakaguchi et al., 2017; Li et al., 2019; Nakashima et al., 2019; Bonanni et al., 2021; Ernst et al., 2021; Wilke et al., 2022). Here, CSNK2B is linked to Poirier-Bienvenu neurodevelopmental syndrome.