For OVID Medline and OVID Embase, we used the following keywords combined with Booleans: Non-alcoholic fatty liver disease OR NAFL OR NAFLD OR metabolic associated fatty liver disease OR MAFLD OR non-alcoholic steatohepatitis OR NASH AND Obeticholic acid OR Ocaliva OR Farnesoid X Receptor Agonists AND GLP-1 agonist OR Ozempic OR Semaglutide. This evidence concerns the gene GCG and metabolic dysfunction-associated steatohepatitis.