For OVID Medline and OVID Embase, we used the following keywords combined with Booleans: Non-alcoholic fatty liver disease OR NAFL OR NAFLD OR metabolic associated fatty liver disease OR MAFLD OR non-alcoholic steatohepatitis OR NASH AND Obeticholic acid OR Ocaliva OR Farnesoid X Receptor Agonists AND GLP-1 agonist OR Ozempic OR Semaglutide. The gene discussed is GLP1R; the disease is metabolic dysfunction-associated steatotic liver disease.