APOE and age: The ε4 allele of the apolipoprotein E gene (ApoE) is a well-established genetic vulnerability factor for pathologic and normal age-related cognitive decline (Todd et al., 2018; Slot et al., 2019; Williams et al., 2019; Yin et al., 2019; Emrani et al., 2020; Montagne et al., 2020).